Surfactant Protein C antibody

Catalog No. ABIN5963704

This anti-Surfactant Protein C antibody is a Rabbit Polyclonal antibody detecting Surfactant Protein C in WB, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for Surfactant Protein C antibody (ABIN5963704)

Target: Surfactant Protein C (SFTPC)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Surfactant Protein C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Surfactant Protein C Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SFTPC (NP_001165881.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Surfactant Protein C

Target: Surfactant Protein C (SFTPC)

Alternative Name: SFTPC

Background: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Molecular Weight:

Observed_MW: 21kDa

Calculated_MW: 20kDa/21kDa

Gene ID: 6440

UniProt: P11686