ACVR2A antibody

Catalog No. ABIN6569024

The Rabbit Polyclonal anti-ACVR2A antibody has been validated for IHC and IF. It is suitable to detect ACVR2A in samples from Human, Mouse and Rat.

Quick Overview for ACVR2A antibody (ABIN6569024)

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR2A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ACVR2A Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human ACVR2A (NP_001607.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ACVR2A

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Alternative Name: ACVR2A

Background: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Molecular Weight:

Observed_MW: 58kDa

Calculated_MW: 45kDa/57kDa

Gene ID: 92

UniProt: P27037