HDAC3 antibody
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- Target See all HDAC3 Antibodies
- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human HDAC3
- Isotype
- IgG
- Top Product
- Discover our top product HDAC3 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 IP 1:50 - 1:200
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- Alternative Name
- HDAC3 (HDAC3 Products)
- Background
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Synonyms: HD3,HDAC 3,HDAC3,HDAC3,Histone deacetylase 3,RPD3 2,RPD3,RPD3-2,SMAP45
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
- Molecular Weight
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Observed_MW: 47kDa
Calculated_MW: 48kDa/49kDa
- Gene ID
- 8841
- UniProt
- O15379
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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