Heparanase 2 antibody (C-Term)

Catalog No. ABIN656918

The Rabbit Polyclonal anti-Heparanase 2 antibody is suitable to detect Heparanase 2 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for Heparanase 2 antibody (C-Term) (ABIN656918)

Target: Heparanase 2 (HPSE2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Heparanase 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32587

Product Details anti-Heparanase 2 Antibody

Binding Specificity: AA 451-480, C-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HPSE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the C-terminal region of human HPSE2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: HPSE2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for Heparanase 2

Target: Heparanase 2 (HPSE2)

Alternative Name: HPSE2

Background: Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.

Molecular Weight: 66596

Gene ID: 60495

NCBI Accession: NP_001159716, NP_001159717, NP_001159718, NP_068600

UniProt: Q8WWQ2

Pathways: Glycosaminoglycan Metabolic Process