APEH antibody

Catalog No. ABIN6570186

This Rabbit Polyclonal antibody specifically detects APEH in WB and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for APEH antibody (ABIN6570186)

Target: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APEH antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-APEH Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human APEH

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IP 1:20 - 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for APEH

Target: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Alternative Name: APEH

Background:

Synonyms: AARE,ACPH,ACPH,Acyl peptide hydrolase,Acyl-peptide hydrolase,Acylamino acid releasing enzyme,Acylamino-acid-releasing enzyme,Acylaminoacyl peptidase,Acylaminoacyl-peptidase,APEH,APH,N acylaminoacyl peptide hydrolase,OPH,Oxidized protein hydrolase

Background: This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Molecular Weight:

Observed_MW: 81kDa

Calculated_MW: 81kDa

Gene ID: 327

UniProt: P13798