GIP antibody

Catalog No. ABIN6570298

The Rabbit Polyclonal anti-GIP antibody is suitable to detect GIP in samples from Human, Rat and Mouse. It has been validated for IHC and IF.

Quick Overview for GIP antibody (ABIN6570298)

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIP antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GIP Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GIP (NP_004114.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GIP

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Alternative Name: GIP

Background: This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.

Molecular Weight:

Observed_MW: 17kDa

Calculated_MW: 17kDa

Gene ID: 2695

UniProt: P09681

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism