CCR8 antibody

Catalog No. ABIN6571534

The Rabbit Polyclonal anti-CCR8 antibody has been validated for WB. It is suitable to detect CCR8 in samples from Human, Mouse and Rat.

Quick Overview for CCR8 antibody (ABIN6571534)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCR8 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CCR8

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Alternative Name: CCR8

Background:

Synonyms: C C chemokine receptor type 8,C C CKR 8,C C motif chemokine receptor 8,C-C chemokine receptor type 8,C-C CKR-8,CC chemokine receptor 8,CC chemokine receptor CHEMR1,CC chemokine receptor type 8,CC CKR 8,CC-CKR-8,CCR 8,CCR-8,Ccr8,CCR8 protein,CCR8-L,CCR8,CDw198,CDw198 antigen,Chemokine (C C motif) receptor 8,Chemokine (C C) receptor 8,Chemokine (C C) receptor like 2,Chemokine (CC motif) receptor 8,Chemokine (CC) receptor 8,Chemokine (CC) receptor like 1,Chemokine (CC) receptor like 2,Chemokine C C motif receptor 8,Chemokine C C receptor 8,Chemokine CC motif receptor 8,Chemokine CC receptor 8,Chemokine receptor 8,Chemokine receptor like 1,Chemokine receptor-like 1,CKR L1,CKR-L1,CKRL 1,CKRL1,CMKBR 8,CMKBR L2,CMKBR8,CMKBRL 2,CMKBRL2,CY 6,CY6,GPR CY6,GPR-CY6,GPRCY6,MGC123958,MGC123959,MGC129966,MGC129973,TER 1,TER1

Background: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

Molecular Weight:

Observed_MW: 41kDa

Calculated_MW: 31kDa/40kDa

Gene ID: 1237

UniProt: P51685