DSPP antibody

Catalog No. ABIN6571738

This Rabbit Polyclonal antibody specifically detects DSPP in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DSPP antibody (ABIN6571738)

Target: DSPP (Dentin Sialophosphoprotein (DSPP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSPP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DSPP Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human DSPP

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DSPP

Target: DSPP (Dentin Sialophosphoprotein (DSPP))

Alternative Name: DSPP

Background:

Synonyms: Dentin phosphophoryn,Dentin phosphoprotein,dentin phosphoryn ,Dentin sialophosphoprotein,Dentin sialophosphoprotein precursor ,Dentin sialoprotein,dentinogenesis imperfecta 1,DFNA39,DGI1,DMP3,DPP,DSP,Dspp,DSPP,DTDP2

Background: This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene.

Molecular Weight:

Observed_MW: 110kDa

Calculated_MW: 131kDa

Gene ID: 1834

UniProt: Q9NZW4