JARID2 antibody

Catalog No. ABIN6572030

This Rabbit Polyclonal antibody specifically detects JARID2 in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for JARID2 antibody (ABIN6572030)

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JARID2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-JARID2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human JARID2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for JARID2

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Alternative Name: JARID2

Background:

Synonyms: JARD2,JARD2,JARID2,JMJ,Jumonji AT rich interactive domain 2 ,Jumonji homolog,Jumonji like protein,Jumonji protein,Jumonji/ARID domain containing protein 2,Jumonji/ARID domain-containing protein 2,Protein Jumonji

Background: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

Molecular Weight:

Observed_MW: 139kDa

Calculated_MW: 106kDa/119kDa/138kDa

Gene ID: 3720

UniProt: Q92833

Pathways: Chromatin Binding