CAPN10 antibody

Catalog No. ABIN6572052

This anti-CAPN10 antibody is a Rabbit Polyclonal antibody detecting CAPN10 in WB. Suitable for Human.

Quick Overview for CAPN10 antibody (ABIN6572052)

Target: CAPN10 (Calpain 10 (CAPN10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPN10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CAPN10 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CAPN10

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:4000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CAPN10

Target: CAPN10 (Calpain 10 (CAPN10))

Alternative Name: CAPN10

Background:

Synonyms: Calcium activated neutral protease,Calcium activated neutral proteinase 10,Calcium-activated neutral proteinase 10,calpain like protease CAPN10,Calpain-10,Calpain10,CAN10,CANP 10,CANP10,CAPN 10,CAPN10,EC 3.4.22.,KIAA1845,NIDDM1

Background: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.

Molecular Weight:

Observed_MW: 75kDa

Calculated_MW: 15kDa/29kDa/49kDa/57kDa/60kDa/74kDa

Gene ID: 11132

UniProt: Q9HC96

Pathways: Positive Regulation of Peptide Hormone Secretion