HuC/ELAVL3 antibody (N-Term)

Catalog No. ABIN657256

This Rabbit Polyclonal antibody specifically detects HuC/ELAVL3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for HuC/ELAVL3 antibody (N-Term) (ABIN657256)

Target: HuC/ELAVL3 (ELAVL3) (ELAV-Like 3 (ELAVL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HuC/ELAVL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33427

Product Details anti-HuC/ELAVL3 Antibody

Binding Specificity: AA 71-99, N-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ELAVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human ELAVL3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for HuC/ELAVL3

Target: HuC/ELAVL3 (ELAVL3) (ELAV-Like 3 (ELAVL3))

Alternative Name: ELAVL3

Background: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molecular Weight: 39547

NCBI Accession: NP_001411, NP_115657

UniProt: Q14576