CD33 antibody (AA 88-117)

Catalog No. ABIN657464

The Rabbit Polyclonal anti-CD33 antibody has been validated for WB. It is suitable to detect CD33 in samples from Human.

Quick Overview for CD33 antibody (AA 88-117) (ABIN657464)

Target: CD33

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD33 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB33637

Product Details anti-CD33 Antibody

Binding Specificity: AA 88-117

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human CD33.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CD33 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for CD33

Target: CD33

Alternative Name: CD33

Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Molecular Weight: 39825

Gene ID: 945

NCBI Accession: NP_001076087, NP_001171079, NP_001763

UniProt: P20138