ZFX antibody (AA 288-317)

Catalog No. ABIN657487

This Rabbit Polyclonal antibody specifically detects ZFX in WB. It exhibits reactivity toward Human.

Quick Overview for ZFX antibody (AA 288-317) (ABIN657487)

Target: ZFX (Zinc Finger Protein, X-Linked (ZFX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFX antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB32448

Product Details anti-ZFX Antibody

Binding Specificity: AA 288-317

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZFX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-317 amino acids from the Central region of human ZFX.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ZFX Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for ZFX

Target: ZFX (Zinc Finger Protein, X-Linked (ZFX))

Alternative Name: ZFX

Background: This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.

Molecular Weight: 90522

Gene ID: 7543

NCBI Accession: NP_001171555, NP_001171556, NP_001171557, NP_003401

UniProt: P17010