Selenoprotein K antibody (AA 32-61)

Catalog No. ABIN657518

The Rabbit Polyclonal anti-Selenoprotein K antibody has been validated for WB. It is suitable to detect Selenoprotein K in samples from Human and Mouse. There is 1 publication available.

Quick Overview for Selenoprotein K antibody (AA 32-61) (ABIN657518)

Target: Selenoprotein K (SELK)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Selenoprotein K antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB32894

Product Details anti-Selenoprotein K Antibody

Binding Specificity: AA 32-61

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the Central region of human SELK.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SELK Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-Selenoprotein K antibody (ABIN657518)

Fredericks, Hoffmann, Rose, Osterheld, Hess, Mercier, Hoffmann: "Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 46, pp. 16478-83, (2014) (PubMed).

Target Details for Selenoprotein K

Target: Selenoprotein K (SELK)

Alternative Name: SELK

Background: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant.

Molecular Weight: 10645

Gene ID: 58515

NCBI Accession: NP_067060

UniProt: Q9Y6D0