CCR10 antibody (N-Term)

Catalog No. ABIN657666

This anti-CCR10 antibody is a Rabbit Polyclonal antibody detecting CCR10 in WB. Suitable for Human.

Quick Overview for CCR10 antibody (N-Term) (ABIN657666)

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR10 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB33732

Product Details anti-CCR10 Antibody

Binding Specificity: AA 1-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCR10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCR10.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CCR10 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for CCR10

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Alternative Name: CCR10

Background: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27, MIM 604833), CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).

Molecular Weight: 38416

Gene ID: 2826

NCBI Accession: NP_057686

UniProt: P46092