IL-6 Receptor antibody (AA 221-270)

Catalog No. ABIN6579241

The Rabbit Polyclonal anti-IL-6 Receptor antibody has been validated for WB and ELISA. It is suitable to detect IL-6 Receptor in samples from Human.

Quick Overview for IL-6 Receptor antibody (AA 221-270) (ABIN6579241)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL-6 Receptor Antibody

Binding Specificity: AA 221-270

Specificity:

IL6R Antibody detects endogenous levels of IL6R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IL6R.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: IL6R

Background:

Synonyms: IL6R, Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80, gp80, CD126

NCBI Gene Symbol: IL6R

Molecular Weight: 51 kDa

Gene ID: 3570

OMIM: 147880

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints