LIM Domain Kinase 1 antibody (C-Term)

Catalog No. ABIN659052

This anti-LIM Domain Kinase 1 antibody is a Mouse Monoclonal antibody detecting LIM Domain Kinase 1 in WB. Suitable for Human and Mouse.

Quick Overview for LIM Domain Kinase 1 antibody (C-Term) (ABIN659052)

Target: LIM Domain Kinase 1 (LIMK1)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This LIM Domain Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 175CT3-2-5

Product Details anti-LIM Domain Kinase 1 Antibody

Binding Specificity: AA 479-508, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This LIMK1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 479-508 amino acids from the C-terminal region of human LIMK1.

Isotype: IgM kappa

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for LIM Domain Kinase 1

Target: LIM Domain Kinase 1 (LIMK1)

Alternative Name: LIMK1

Background: Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.

Molecular Weight: 72585

Gene ID: 3984

NCBI Accession: NP_001191355, NP_002305

UniProt: P53667

Pathways: Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events