TGFB2 antibody

Catalog No. ABIN659106

This anti-TGFB2 antibody is a Mouse Monoclonal antibody detecting TGFB2 in WB, IHC (p) and IF. Suitable for Human.

Quick Overview for TGFB2 antibody (ABIN659106)

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGFB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: 220ct16-4-3-1

Product Details anti-TGFB2 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This TGFB2 monoclonal antibody is generated from mouse immunized with TGFB2 recombinant protein.

Isotype: IgG1 kappa

Application Details

Application Notes: IF: 1:10~50. WB: 1:100~1000. WB: 1:500-1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50. IHC: 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TGFB2

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Alternative Name: TGFB2

Background: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 47748

Gene ID: 7042

NCBI Accession: NP_001129071, NP_003229

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus