DDR2 antibody (AA 801-855)

Catalog No. ABIN6654123

This Rabbit Polyclonal antibody specifically detects DDR2 in WB, ELISA and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for DDR2 antibody (AA 801-855) (ABIN6654123)

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DDR2 Antibody

Binding Specificity: AA 801-855

Purification: Antigen affinity purified

Immunogen: Amino acids T801-E855 from the human protein were used as the immunogen for the DDR2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DDR2 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 2-3 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant human protein)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the DDR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for DDR2

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Alternative Name: DDR2

Background: Discoidin domain-containing receptor 2, also known as CD167b (cluster of differentiation 167b), is a protein that in humans is encoded by the DDR2 gene. This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.

UniProt: Q16832

Pathways: RTK Signaling