beta Catenin antibody (AA 2-233)
Quick Overview for beta Catenin antibody (AA 2-233) (ABIN6654150)
Target
See all beta Catenin (CATNB) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 2-233
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Purification
- Protein G affinity
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Immunogen
- Human beta Catenin recombinant protein (amino acids A2-K233) was used as the immunogen for the Beta Catenin antibody.
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Isotype
- IgG1
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Application Notes
- Optimal dilution of the Beta Catenin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ICC: 2-4 μg/mL,FACS: 1-3 μg/10^6 cells
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- -20 °C
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Storage Comment
- After reconstitution, the Beta Catenin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Alternative Name
- Beta Catenin
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Background
- Catenins are proteins found in complexes with cadherin cell adhesion molecules of animal cells. The first two catenins that were identified became known as alpha-catenin and beta-catenin. Alpha-catenin can bind to beta-catenin and can also bind actin. Beta-catenin binds the cytoplasmic domain of some cadherins. Beta-catenin is an adherens junction protein. It plays an important role in various aspects of liver biology including liver development (both embryonic and postnatal), liver regeneration following partial hepatectomy. HGF-induced hepatpomegaly, liver zonation, and pathogenesis of liver cancer.
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UniProt
- P35222
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Pathways
- Peptide Hormone Metabolism
Target
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