ADRP antibody

Catalog No. ABIN6654241

The Rabbit Monoclonal anti-ADRP antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect ADRP in samples from Human.

Quick Overview for ADRP antibody (ABIN6654241)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ADRP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ADFP-2755R

Product Details anti-ADRP Antibody

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: A portion of amin acids 249-376 from the human protein were used as the immunogen for this recombinant Adipophilin antibody.

Isotype: IgG kappa

Application Details

Application Notes: Titering of the recombinant Adipophilin antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. ELISA: order formulation without BSA for coating,Immunohistochemistry (FFPE): 1-2 μg/mL,Prediluted IHC only format: incubate for 30 min at RT (1),Western blot: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: The recombinant Adipophilin antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Alternative Name: Adipophilin / Perilipin 2 / ADRP / PLIN2

Background: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism