MVP antibody

Catalog No. ABIN6654407

The Rabbit Monoclonal anti-MVP antibody (Clone MJVP-1R) (ABIN6654407) specifically detects MVP in IHC (p). The antibody is reactive with Human samples.

Quick Overview for MVP antibody (ABIN6654407)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MVP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MJVP-1R

Product Details anti-MVP Antibody

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for the recombinant MVP antibody.

Isotype: IgG kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the recombinant MVP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant MVP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: MVP / Major Vault Protein

Background: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases. [UniProt]