ICAM-3/CD50 antibody

Catalog No. ABIN6654485

This anti-ICAM-3/CD50 antibody is a Rabbit Monoclonal antibody detecting ICAM-3/CD50 in IHC (p). Suitable for Human.

Quick Overview for ICAM-3/CD50 antibody (ABIN6654485)

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ICAM-3/CD50 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ICAM3-2873R

Product Details anti-ICAM-3/CD50 Antibody

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: Full length recombinant human protein was used as the immunogen for the recombinant ICAM3 antibody.

Isotype: IgG kappa

Application Details

Application Notes: Optimal dilution of the recombinant ICAM3 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant ICAM3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for ICAM-3/CD50

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Alternative Name: ICAM-3 / CD50

Background: Recognizes an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.