IFITM1 antibody (N-Term)

Catalog No. ABIN6655560

Supplier Product No.: 600-401-p72

This Rabbit Polyclonal antibody specifically detects IFITM1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for IFITM1 antibody (N-Term) (ABIN6655560)

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IFITM1 Antibody

Binding Specificity: N-Term

Supplier Product No.: 600-401-p72

Supplier: Rockland

Purpose: IFITM1 Antibody

Cross-Reactivity (Details): Anti-IFITM1 antibody is directed against human IFITM1 protein.

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: IFITM1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the N-terminal of human IFITM1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry_Dilution: 1:100-1:500

Western_Blot_Dilution: 0.5 μg/mL

Comment:

Anti-IFITM1 is tested for Immunohistochemistry-P, -F, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~14 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Preservative: 0.05 mg Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for IFITM1

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Alternative Name: IFITM1

Background:

Synonyms: Dispanin subfamily A member 2a,

Background: Interferon-induced Transmembrane Protein 1 (IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth. This antibody is suitable for researchers interested in cancer and stem cell research.

Gene Name: IFITM1

Gene ID: 8519

NCBI Accession: NP_003632

UniProt: P13164