KDM4B antibody (Internal Region)

Catalog No. ABIN6655562

Supplier Product No.: 100-401-v90

This anti-KDM4B antibody is a Rabbit Polyclonal antibody detecting KDM4B in WB, ELISA, IF and FM. Suitable for Human.

Quick Overview for KDM4B antibody (Internal Region) (ABIN6655562)

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM)

Product Details anti-KDM4B Antibody

Binding Specificity: Internal Region

Supplier Product No.: 100-401-v90

Supplier: Rockland

Purpose: JMJD2B Antibody

Cross-Reactivity (Details): Cross reactivity with JMJD2b from other species not tested.

Purification: Anti-JMJD2b Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Sterility: Sterile filtered

Immunogen: Anti-JMJD2B Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of human JMJD2b.

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:200

IF_Microscopy_Dilution: 1:200

Western_Blot_Dilution: 1:1,000

Comment:

Anti-JMJD2B Antibody has been tested by ELISA, Immunofluorescence and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 120 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for KDM4B

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Alternative Name: JMJD2b

Background:

Synonyms: Lysine-specific demethylase 4B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B

Background: JMJD2b, belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2b specifically demethylates the trimethylated K9 of histone H3. It is not able to demethylate K4, K27 and K36 of histone H3, nor K20 of histone H4. Anti-JMJD2b Antibody is ideal for research in Epigenetics and Chromatin Remodeling.

Gene Name: KDM4B

Gene ID: 23030

NCBI Accession: NP_055830

UniProt: O94953

Pathways: Warburg Effect