DDC antibody (N-Term)

Catalog No. ABIN6655667

Supplier Product No.: 600-401-x02

This anti-DDC antibody is a Rabbit Polyclonal antibody detecting DDC in WB and ELISA. Suitable for Human.

Quick Overview for DDC antibody (N-Term) (ABIN6655667)

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DDC Antibody

Binding Specificity: N-Term

Supplier Product No.: 600-401-x02

Supplier: Rockland

Purpose: DOPA Decarboxylase Antibody

Purification: Anti-DOPA Decarboxylase Antibody was prepared from rabbit serum by affinity purification using an AminoLink® Plus column matrix to which purified recombinant bovine DDC was coupled.

Sterility: Sterile filtered

Immunogen: Anti-DOPA Decarboxylase Antibody was produced in rabbits by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the N-terminal region of human DOPA decarboxylase (DDC) conjugated to KLH (keyhole limpet hemocyanin).

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Comment:

Anti-DOPA Decarboxylase Antibody is suitable for Western Blots and is specific for the ~55 kDa DDC protein. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Preservative: None

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Alternative Name: DOPA Decarboxylase

Background:

Synonyms: Aromatic-L-amino-acid decarboxylase, AADC, DDC

Background: DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC, DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin. It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. DOPA Decarboxylase Antibody is ideal for researchers interested in neuroscience research.

Gene Name: DDC

Gene ID: 1644

NCBI Accession: NP_000781

UniProt: P20711

Pathways: Dopaminergic Neurogenesis