QKI antibody (AA 1-341) (PE)

Catalog No. ABIN6656355

Supplier Product No.: 200-308-w79

This Mouse Monoclonal antibody specifically detects QKI in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for QKI antibody (AA 1-341) (PE) (ABIN6656355)

Target: QKI (Protein Quaking (QKI))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This QKI antibody is conjugated to PE

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: S147-6

Product Details anti-QKI Antibody (PE)

Binding Specificity: AA 1-341

Supplier Product No.: 200-308-w79

Supplier: Rockland

Purpose: QKI (pan) Antibody Phycoerythrin

Cross-Reactivity (Details): BLAST analysis suggests that it is 100 % identical to mouse, 99 % identical to rat and 90 % identical to QKI-6, QKI-7 and QKI-7b.

Purification: Anti-QKI (pan) Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: Anti-QKI (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-341 (full length) of human QKI-5.

Isotype: IgG2b

Application Details

Application Notes:

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Comment:

Anti-QKI (pan) R-PE Conjugated Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~36-38kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Expiry Date: 12 months

Target Details for QKI

Target: QKI (Protein Quaking (QKI))

Alternative Name: QKI

Background:

Synonyms: Protein quaking, Hqk, HqkI, QKI, KH Domain Containing, RNA Binding (QKI)

Background: QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be downregulated in the brain of schizophrenic patients. Anti-QKI (pan) is ideal for research in Neuroscience and Gene Expression.

Gene Name: QKI-5

Gene ID: 9444

UniProt: Q96PU8