Dynamin 1 antibody (N-Term)

Catalog No. ABIN6657461

Supplier Product No.: 600-401-d31

This anti-Dynamin 1 antibody is a Rabbit Polyclonal antibody detecting Dynamin 1 in WB and ELISA. Suitable for Human.

Quick Overview for Dynamin 1 antibody (N-Term) (ABIN6657461)

Target: Dynamin 1 (DNM1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Dynamin 1 Antibody

Binding Specificity: N-Term

Supplier Product No.: 600-401-d31

Supplier: Rockland

Purpose: Dynamin Antibody

Cross-Reactivity (Details): Anti-Dynamin antibody is directed against human Dynamin.

Purification: Anti-Dynamin antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Dynamin Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Comment:

Anti-Dynamin Antibody is tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 95 kDa in size corresponding to the dynamin proteins in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for Dynamin 1

Target: Dynamin 1 (DNM1)

Alternative Name: Dynamin

Background:

Synonyms: Dynamin-1, B-dynamin, D100

Background: Dynamin Antibody detects Dynamin which is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis. There are 3 known isofoms of Dynamin, each having several splice variants as well. Dynamin I is expressed only in neurons whereas Dynamin II is ubiquitously expressed and Dynamin III is found primarily in the testes. Dynamin 1 is phosphorylated by PKC and dephosphorylated by calcineurin. Anti-Dynamin Antibody is ideal for investigators involved in Cell Signaling, Cell Motility, Neuroscience and Cancer Research.

Gene Name: DNM1

Gene ID: 1759

UniProt: Q05193

Pathways: Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling