Periostin antibody

Catalog No. ABIN6657609

Supplier Product No.: 600-401-e10

This Rabbit Polyclonal antibody specifically detects Periostin in WB and IHC. It exhibits reactivity toward Mouse.

Quick Overview for Periostin antibody (ABIN6657609)

Target: Periostin (POSTN)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Periostin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Periostin Antibody

Supplier Product No.: 600-401-e10

Supplier: Rockland

Purpose: Periostin Antibody

Cross-Reactivity (Details): Anti-Periostin antibody is directed against mouse Periostin protein.

Purification: This antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Periostin Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the fasciclin domain 1 of mouse periostin.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry_Dilution: 1:100

Western_Blot_Dilution: 1:1000

Other: User Optimized

Comment:

Anti-Periostin Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a three bands of approximately 93 kDa in size corresponding to periostin pan proteins in mouse lung extract. The antibody is suitable for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90° C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20).

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for Periostin

Target: Periostin (POSTN)

Alternative Name: Periostin

Background:

Synonyms: PN, Osteoblast-specific factor 2, OSF-2

Background: Periostin Antibody detects Periostin protein. Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium. Anti-Periostin Antibody is ideal for investigators involved in Cancer and Cardiovascular research.

Gene Name: POSTN

Gene ID: 50706

UniProt: Q62009