AHSA1 antibody

Catalog No. ABIN6657694

Supplier Product No.: 100-401-e82

The Rabbit Polyclonal anti-AHSA1 antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect AHSA1 in samples from Mouse. There is 1 publication available.

Quick Overview for AHSA1 antibody (ABIN6657694)

Target: AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHSA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-AHSA1 Antibody

Supplier Product No.: 100-401-e82

Supplier: Rockland

Purpose: Aha1 Antibody

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with Aha 1 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Purification: Anti-Aha 1 Antibody was purified by Protein A chromatography.

Sterility: Sterile filtered

Immunogen: Aha1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with Mouse Aha1.

Isotype: IgG

Application Details

Application Notes:

Immunoprecipitation_Dilution: User Optimized

ELISA_Dilution: 1:200

Immunohistochemistry_Dilution: 1:1000

Western_Blot_Dilution: 0.5-1:1000

Comment:

Anti-Aha1 Antibody has been tested in western blot, ICC, and IHC and is suitable for use in ELISA, IF microscopy and IP. Expect a band approximately ~38kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

References for anti-AHSA1 antibody (ABIN6657694)

Jinwal, Koren, Dickey: "Reconstructing the Hsp90/Tau Machine." in: Current enzyme inhibition, Vol. 9, Issue 1, pp. 41-45, (2013) (PubMed).

Target Details for AHSA1

Target: AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))

Alternative Name: Aha1

Background:

Synonyms: Aha1, SHSA1, HspC322, p38, Activator of 90 kDa heat shock protein ATPase homolog 1

Background: Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding. It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors.

Gene Name: Ahsa1

Gene ID: 217737

NCBI Accession: NP_666148

UniProt: Q8BK64