Retinoid X Receptor beta antibody

Catalog No. ABIN6657988

Supplier Product No.: 200-301-e27

The Mouse Monoclonal anti-Retinoid X Receptor beta antibody has been validated for WB. It is suitable to detect Retinoid X Receptor beta in samples from Mouse.

Quick Overview for Retinoid X Receptor beta antibody (ABIN6657988)

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoid X Receptor beta antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 147

Product Details anti-Retinoid X Receptor beta Antibody

Supplier Product No.: 200-301-e27

Supplier: Rockland

Purpose: Retinoid X Receptor beta Antibody

Cross-Reactivity (Details): Retinoid X Receptor beta antibodies are Protein G purified from cell culture supernatant.

Purification: Anti-Retinoid X Receptor beta antibody is directed against RXR-β.

Immunogen: Anti-Retinoid X Receptor b-Isotype Monoclonal Antibody was produced in mouse by repeated immunizations with Retinoid X Receptor- Synthetic peptide corresponding to amino acid residues from the reported hinge region.

Isotype: IgG1

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:1000

Comment:

Anti-Retinoid X Receptor beta antibody has been tested by Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 48 kDa in size corresponding to the RXR-β protein in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Alternative Name: Retinoid X Receptor beta

Background:

Synonyms: Nuclear receptor subfamily 2 group B member 2, Retinoid X receptor beta, RXR-β

Background: Retinoid X Receptor beta antibody detects RXR-β. The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors. Anti-Retinoid X Receptor beta antibody is ideal for investigators involved in Cancer, Neuroscience, Signal Transduction research.

Gene Name: RXRB

Gene ID: 6257

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway