Cnpase antibody

Catalog No. ABIN6658047

Supplier Product No.: 100-401-d21

This Rabbit Polyclonal antibody specifically detects Cnpase in WB, IHC and ELISA. It exhibits reactivity toward Rabbitand has been mentioned in 1 publication.

Quick Overview for Cnpase antibody (ABIN6658047)

Target: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Reactivity: Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cnpase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Cnpase Antibody

Supplier Product No.: 100-401-d21

Supplier: Rockland

Purpose: CNPase Antibody

Cross-Reactivity (Details): Anti-CNP antibody is directed against rabbit CNP.

Purification: The antibody was prepared as neat antiserum by delipdation and defibrination from monospecific antiserum.

Immunogen: Anti-CNP Antibody was produced in rabbit by repeated immunizations with endogenous rabbit 2,3 cyclic nucleotide-3-phospho-diesterase

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: 1:1000

Western_Blot_Dilution: 1:1000

Comment:

Anti-CNP has been tested in western blot and IHC and is suitable for usage in ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a 46kDa band by western blot corresponding to CNP protein in the appropriate cell lysate of tissue.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

References for anti-Cnpase antibody (ABIN6658047)

Hirose-Ikeda, Chu, Zhao, Akil, Escalante, Vergnes, Cepeda, Espinosa-Jeffrey: "Trophic factors are essential for the survival of grafted oligodendrocyte progenitors and for neuroprotection after perinatal excitotoxicity." in: Neural regeneration research, Vol. 15, Issue 3, pp. 557-568, (2020) (PubMed).

Target Details for Cnpase

Target: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Alternative Name: CNPase

Background:

Synonyms: CNPase

Background: CNP antibody recognizes CNP or 2,3-cyclic nucleotide-3-phosphodiesterase which is a membrane bound, microtubule associated protein that is among the most abundant myelin proteins of the CNS. It is thought that CNP may serve as a regulator of tubulin polymerization and of microtubule distribution. It was recently found that CNP may also function as a possible linker protein anchoring microtubules to the plasma membrane via a 13 residue C-terminal CNP fragment. Anti-CNP antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: CNP

UniProt: G1T512