RAB3A antibody (N-Term)

Catalog No. ABIN6658250

Supplier Product No.: 612-401-e20

This anti-RAB3A antibody is a Rabbit Polyclonal antibody detecting RAB3A in WB. Suitable for Rat.

Quick Overview for RAB3A antibody (N-Term) (ABIN6658250)

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB3A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAB3A Antibody

Binding Specificity: N-Term

Supplier Product No.: 612-401-e20

Supplier: Rockland

Purpose: Rab3 Antibody

Cross-Reactivity (Details): This antibody is directed against rat Rab3 proteins.

Purification: Anti-Rab 3 antibodies was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Rab 3 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.

Isotype: IgG

Application Details

Application Notes:

Western_Blot_Dilution: 1:1000

Other: User Optimized

Comment:

Anti-Rab 3 (Rabbit) antibody is tested for use in Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 27 kDa in size corresponding to Rab3 protein in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for RAB3A

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Alternative Name: Rab 3

Background:

Synonyms: Ras-related protein Rab-3A

Background: Rab 3 Antibody detects Rab 3 which belongs to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab3's are thought to play a key role in presynaptic vesicle trafficking and priming.

Gene Name: RAB3A

Gene ID: 25531

NCBI Accession: NP_037150

UniProt: P63012

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport