MMP3 antibody (AA 401-477)

Catalog No. ABIN668301

This anti-MMP3 antibody is a Rabbit Polyclonal antibody detecting MMP3 in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). Suitable for Human, Rat, Mouse and Rabbit. This Primary Antibody has been cited in 8+ publications.

Quick Overview for MMP3 antibody (AA 401-477) (ABIN668301)

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Reactivity: Human, Rat, Mouse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MMP3 Antibody

Binding Specificity: AA 401-477

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Predicted Reactivity: Dog,Sheep,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MMP3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MMP3 antibody (ABIN668301)

Xie, Huo, Li, Dai, Xu, Yin: "Olfactory Ensheathing Cells Inhibit Gliosis in Retinal Degeneration by Downregulation of the Müller Cell Notch Signaling Pathway." in: Cell transplantation, Vol. 26, Issue 6, pp. 967-982, (2018) (PubMed).

Wang, Chen, Tang, Jiang, Ji: "AMD3100 Attenuates Matrix Metalloprotease-3 and -9 Expressions and Prevents Cartilage Degradation in a Monosodium Iodo-Acetate-Induced Rat Model of Temporomandibular Osteoarthritis." in: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, Vol. 74, Issue 5, pp. 927.e1-927.e13, (2016) (PubMed).

Yang, Lu, Guo: "Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis." in: Molecular medicine reports, Vol. 14, Issue 5, pp. 4075-4082, (2016) (PubMed).

Wei, Zhong, Wang, Zhou, Pan, Cui, Sun, Zou, Gao, Jiang, Chen, Zhuang, Sun, Liu: "Pingyangmycin-induced in vivo lumbar disc degeneration model of rhesus monkeys." in: Spine, Vol. 40, Issue 4, pp. E199-210, (2015) (PubMed).

Koch, Hammer, Ossmann, Schierle, Sack, Hofmann, Wecks, Boldt: "Tissue Engineering of Ureteral Grafts: Preparation of Biocompatible Crosslinked Ureteral Scaffolds of Porcine Origin." in: Frontiers in bioengineering and biotechnology, Vol. 3, pp. 89, (2015) (PubMed).

Luo, Zhang, Wang, Hu, Song, Zhang: "The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model." in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, (2014) (PubMed).

Luo, Zhang, Wang, Hu, Song, Su, Zhang: "Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats." in: Bone, Vol. 55, Issue 2, pp. 439-48, (2013) (PubMed).

Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: "The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage." in: Cells, tissues, organs, Vol. 196, Issue 3, pp. 241-50, (2012) (PubMed).

Target Details for MMP3

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Alternative Name: MMP-3

Background:

Synonyms: SL-1, STMY, STR1, CHDS6, MMP-3, STMY1, Stromelysin-1, Matrix metalloproteinase-3, Transin-1, MMP3

Background: Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.

Gene ID: 4314

UniProt: P08254