TSH receptor antibody (PE-Cy5)

Catalog No. ABIN668913

This anti-TSH receptor antibody is a Rabbit Polyclonal antibody detecting TSH receptor in WB and FACS. Suitable for Human, Mouse, Rat, Dog, Pig and Chicken.

Quick Overview for TSH receptor antibody (PE-Cy5) (ABIN668913)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reactivity: Human, Mouse, Rat, Dog, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSH receptor antibody is conjugated to PE-Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-TSH receptor Antibody (PE-Cy5)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSHR

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSHR

Background:

Synonyms: LGR3, CHNG1, hTSHR-I, Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R, TSHR

Background: Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).

Gene ID: 7253

UniProt: P16473

Pathways: Thyroid Hormone Synthesis