TSH receptor antibody (PE-Cy7)

Catalog No. ABIN668914

This Rabbit Polyclonal antibody specifically detects TSH receptor in WB and FACS. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig and Chicken.

Quick Overview for TSH receptor antibody (PE-Cy7) (ABIN668914)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reactivity: Human, Mouse, Rat, Dog, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSH receptor antibody is conjugated to PE-Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-TSH receptor Antibody (PE-Cy7)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSHR

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSHR

Background:

Synonyms: LGR3, CHNG1, hTSHR-I, Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R, TSHR

Background: Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).

Gene ID: 7253

UniProt: P16473

Pathways: Thyroid Hormone Synthesis