RGS2 antibody (AA 116-211) (HRP)

Catalog No. ABIN669300

This anti-RGS2 antibody is a Rabbit Polyclonal antibody detecting RGS2 in ELISA, IHC (p) and IHC (fro). Suitable for Human and Rat.

Quick Overview for RGS2 antibody (AA 116-211) (HRP) (ABIN669300)

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RGS2 Antibody (HRP)

Binding Specificity: AA 116-211

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RGS2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RGS2

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Alternative Name: RGS2

Background:

Synonyms: GS8, Regulator of G-protein signaling 2, RGS2, Cell growth-inhibiting gene 31 protein, G/G1 switch regulatory protein 8, GIG31

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.

Gene ID: 5997

UniProt: P41220

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation