MFN1 antibody (AA 651-741)

Catalog No. ABIN670071

This anti-MFN1 antibody is a Rabbit Polyclonal antibody detecting MFN1 in WB, ELISA, FACS and IHC (p). Suitable for Mouse, Rat, Rabbit and Chicken. This Primary Antibody has been cited in 3+ publications.

Quick Overview for MFN1 antibody (AA 651-741) (ABIN670071)

Target: MFN1 (Mitofusin 1 (MFN1))

Reactivity: Mouse, Rat, Rabbit, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MFN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MFN1 Antibody

Binding Specificity: AA 651-741

Cross-Reactivity: Chicken, Mouse, Rabbit, Rat

Predicted Reactivity: Human,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Mfn 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MFN1 antibody (ABIN670071)

Ku, Ji, Zhang, Li, Sang: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." in: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).

Qin, Deng, Lou, Yu, Pei, Guan et al.: "The decreased expression of mitofusin-1 and increased fission-1 together with alterations in mitochondrial morphology in the kidney of rats with chronic fluorosis may involve elevated oxidative ..." in: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), (2014) (PubMed).

Lou, Guan, Liu, Liu, Zhang, Pan, Pei: "The influence of chronic fluorosis on mitochondrial dynamics morphology and distribution in cortical neurons of the rat brain." in: Archives of toxicology, Vol. 87, Issue 3, pp. 449-57, (2013) (PubMed).

Target Details for MFN1

Target: MFN1 (Mitofusin 1 (MFN1))

Alternative Name: Mfn1

Background:

Synonyms: hfzo1, hfzo2, Mitofusin-1, Fzo homolog, Transmembrane GTPase MFN1, MFN1

Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.

Gene ID: 55669

UniProt: Q8IWA4