Slco1a1 antibody (AA 2-90)

Catalog No. ABIN670791

Cited in 5+ publications. The Rabbit Polyclonal anti-Slco1a1 antibody (ABIN670791) specifically detects Slco1a1 in WB, IF (cc), IF (p), IHC (fro) and IHC (p). The antibody is reactive with Rat and Mouse samples.

Quick Overview for Slco1a1 antibody (AA 2-90) (ABIN670791)

Target: Slco1a1 (Solute Carrier Organic Anion Transporter Family, Member 1a1 (Slco1a1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Slco1a1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Slco1a1 Antibody

Binding Specificity: AA 2-90

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Slco1a1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Slco1a1 antibody (ABIN670791)

Zhu, Dong, Na, Han, Wei, Chen: "Saponins extracted from Dioscorea collettii rhizomes regulate the expression of urate transporters in chronic hyperuricemia rats." in: Biomedicine & pharmacotherapy, Vol. 93, pp. 88-94, (2017) (PubMed).

Pang, Fang, Chen, Zhu, Shan, Su, Yu, Li, Yang, Chen, Liang, Hu, Lv: "Gypenosides Inhibits Xanthine Oxidoreductase and Ameliorates Urate Excretion in Hyperuricemic Rats Induced by High Cholesterol and High Fat Food (Lipid Emulsion)." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 1129-1140, (2017) (PubMed).

Enoki, Watanabe, Arake, Sugimoto, Imafuku, Tominaga, Ishima, Kotani, Nakajima, Tanaka, Matsushita, Fukagawa, Otagiri, Maruyama: "Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1." in: Scientific reports, Vol. 6, pp. 32084, (2016) (PubMed).

Xu, Zhu, Chan, Lu, Shen, Gillies, Zhou: "The Altered Renal and Hepatic Expression of Solute Carrier Transporters (SLCs) in Type 1 Diabetic Mice." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120760, (2015) (PubMed).

Target Details for Slco1a1

Target: Slco1a1 (Solute Carrier Organic Anion Transporter Family, Member 1a1 (Slco1a1))

Alternative Name: Slco1a1

Background:

Synonyms: Oatp1, OATP-1, Slc21a1, Slc21a3, Solute carrier organic anion transporter family member 1A1, Organic anion-transporting polypeptide 1, Sodium-independent organic anion transporter 1, Solute carrier family 21 member 1, Slco1a1, Oatp1a1

Background: Mediates the Na(+)-independent transport of organic anions such as bromosulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids.

Gene ID: 50572

UniProt: P46720