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MRP1 antibody (AA 501-600)

MRP1 Reactivity: Human, Rat WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN671526
  • Target See all MRP1 Antibodies
    MRP1 (Macrophage Inflammatory Protein Related Protein 1 (MRP1))
    Binding Specificity
    • 15
    • 1
    • 1
    • 1
    AA 501-600
    Reactivity
    • 26
    • 19
    • 5
    Human, Rat
    Host
    • 28
    • 1
    Rabbit
    Clonality
    • 22
    • 7
    Polyclonal
    Conjugate
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MRP1 antibody is un-conjugated
    Application
    • 20
    • 13
    • 12
    • 12
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Cow,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse MRP1
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

    Yan, Xie, Li, Zhang, Ma, Xie, Li, Zhong: "Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells." in: Neuropathology : official journal of the Japanese Society of Neuropathology, (2013) (PubMed).

    Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

  • Target
    MRP1 (Macrophage Inflammatory Protein Related Protein 1 (MRP1))
    Alternative Name
    MRP1 (MRP1 Products)
    Synonyms
    Abcc1a antibody, Avcc1a antibody, Mrp antibody, Mrp1 antibody, BTCC-1 antibody, DRAP-27 antibody, MIC3 antibody, MRP-1 antibody, TSPAN-29 antibody, TSPAN29 antibody, Scya6 antibody, c10 antibody, ATP binding cassette subfamily C member 1 antibody, CD9 molecule antibody, chemokine (C-C motif) ligand 6 antibody, Abcc1 antibody, CD9 antibody, Ccl6 antibody
    Background

    Synonyms: MRP, Mrp1, Mdrap, Abcc1a, Abcc1b, Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, LTC4 transporter, Abcc1

    Background: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

    Gene ID
    17250
    UniProt
    O35379
    Pathways
    Response to Water Deprivation, Cell-Cell Junction Organization
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