Multidrug-Resistance Like Protein 1 antibody (AA 501-600)

Catalog No. ABIN671526

This anti-Multidrug-Resistance Like Protein 1 antibody is a Rabbit Polyclonal antibody detecting Multidrug-Resistance Like Protein 1 in WB, FACS, IF (cc), IF (p), ELISA, IHC (p) and IHC (fro). Suitable for Human and Rat. This Primary Antibody has been cited in 3+ publications.

Quick Overview for Multidrug-Resistance Like Protein 1 antibody (AA 501-600) (ABIN671526)

Target: Multidrug-Resistance Like Protein 1 (MRP)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Multidrug-Resistance Like Protein 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Multidrug-Resistance Like Protein 1 Antibody

Binding Specificity: AA 501-600

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse MRP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Multidrug-Resistance Like Protein 1 antibody (ABIN671526)

Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

Yan, Xie, Li, Zhang, Ma, Xie, Li, Zhong: "Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells." in: Neuropathology : official journal of the Japanese Society of Neuropathology, (2013) (PubMed).

Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

Target Details for Multidrug-Resistance Like Protein 1

Target: Multidrug-Resistance Like Protein 1 (MRP)

Alternative Name: MRP1

Background:

Synonyms: MRP, Mrp1, Mdrap, Abcc1a, Abcc1b, Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, LTC4 transporter, Abcc1

Background: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

Gene ID: 17250

UniProt: O35379