PPID antibody (AA 306-370) (DyLight 550)

Catalog No. ABIN7354726

This Rabbit Polyclonal antibody specifically detects PPID in FACS. It exhibits reactivity toward Human.

Quick Overview for PPID antibody (AA 306-370) (DyLight 550) (ABIN7354726)

Target: PPID (Peptidylprolyl Isomerase D (PPID))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPID antibody is conjugated to DyLight 550

Application: Flow Cytometry (FACS)

Product Details anti-PPID Antibody (DyLight 550)

Binding Specificity: AA 306-370

Purpose: Anti-Human PPID DyLight® 550 conjugated Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Human PPID DyLight® 550 conjugated Antibody (ABIN5693052)-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human PPID recombinant protein (Position: N306-A370).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Kieffer, L. J., Thalhammer, T., Handschumacher, R. E.Isolation and characterization of a 40- kDa cyclophilin-related protein.J. Biol. Chem. 267: 5503-5507, 1992. 2. Ratajczak, T., Woollatt, E., Kumar, P., Ward, B. K., Minchin, R. F., Baker, E.Cyclophilin 40 (PPID) gene map position 4q31.3.Chromosome Res. 5: 151 only, 1997. 3. Yokoi, H., Shimizu, Y., Anazawa, H., Lefebvre, C. A., Korneluk, R. G., Ikeda, J.-E.The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene.Genomics 35: 448-455, 1996.

Comment:

Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Target Details for PPID

Target: PPID (Peptidylprolyl Isomerase D (PPID))

Alternative Name: PPID

Background:

Synonyms: Peptidyl-prolyl cis-trans isomerase D, PPIase D

Tissue Specificity: Widely expressed.

Background: Cyclophilin D, Peptidylprolyl isomerase D, also known as PPID, is an enzyme which in humans is encoded by the PPID gene. The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. The Cyclophilin D (PPID) gene contains 10 exons and spans 14.2 kb of genomic DNA. By fluorescence in situ hybridization, the PPID gene is mapped to chromosome 4q31.3. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant ciclosporin.

Molecular Weight: 39 kDa

Gene ID: 5481

UniProt: Q08752

Pathways: Nuclear Hormone Receptor Binding