TIMM17A antibody

Catalog No. ABIN6719637

The Rabbit Polyclonal anti-TIMM17A antibody (ABIN6719637) specifically detects TIMM17A in WB, IHC, IF, IHC (fro), ICC and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TIMM17A antibody (ABIN6719637)

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM17A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-TIMM17A Antibody

Purpose: Anti-TIMM17A Antibody

Sequence: LFSMIDCSMV QVRGKED

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TIMM17A Antibody (ABIN6719637). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TIMM17A, which shares 88.2% and 82.4% amino acid (aa) sequence identity with mouse and rat TIMM17A, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells

Comment:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for TIMM17A

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Alternative Name: TIMM17A

Background:

Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17

Background: Mitochondrial import inner membrane translocase subunit Tim17-A is an enzyme that in humans is encoded by the TIMM17A gene. It is mapped to 1q32.1. TIM17 is a conserved suppressor of mtDNA instability, and overexpression of TIMM17A can prevent mtDNA loss in a human cellular model of mitochondrial disease.

Molecular Weight: 18 kDa

Gene ID: 10440

UniProt: Q99595