LDLR antibody (AA 781-860) (Cy3)

Catalog No. ABIN672114

This anti-LDLR antibody is a Rabbit Polyclonal antibody detecting LDLR in WB, FACS and IF (p). Suitable for Human, Mouse, Rat, Hamster and Plant.

Quick Overview for LDLR antibody (AA 781-860) (Cy3) (ABIN672114)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity: Human, Mouse, Rat, Hamster, Plant

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDLR antibody is conjugated to Cy3

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-LDLR Antibody (Cy3)

Binding Specificity: AA 781-860

Cross-Reactivity: Hamster, Human, Mouse, Plant, Rat

Cross-Reactivity (Details): Hamster

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LDL-R

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDL receptor

Background:

Synonyms: FH, FHC, LDLCQ2, Low-density lipoprotein receptor, LDL receptor, LDLR

Background: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

Gene ID: 3949

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism