IL-10RA antibody (PE)

Catalog No. ABIN6721458

This anti-IL-10RA antibody is a Rat Monoclonal antibody detecting IL-10RA in FACS. Suitable for Mouse.

Quick Overview for IL-10RA antibody (PE) (ABIN6721458)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10RA antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 1B1-3A

Product Details anti-IL-10RA Antibody (PE)

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Alternative Name: CD210

Background:

Synonyms: Interleukin-10 receptor subunit alpha,Il10ra,IL-10 receptor subunit alpha, IL-10R subunit alpha,IL-10RA,CDw210a,Interleukin-10 receptor subunit 1,IL-10R subunit 1,IL-10R1,CD210,Il10ra

Background: CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.

Gene ID: 16154

UniProt: Q61727

Pathways: Growth Factor Binding