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COL2 antibody (AA 1201-1300)

COL2 Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig WB, ELISA, IHC (p), IHC (fro), FACS, IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN672171
  • Target See all COL2 Antibodies
    COL2 (Collagen, Type II (COL2))
    Binding Specificity
    • 15
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1201-1300
    Reactivity
    • 44
    • 32
    • 28
    • 22
    • 17
    • 13
    • 11
    • 4
    • 1
    Human, Mouse, Rat, Rabbit, Guinea Pig
    Host
    • 41
    • 13
    • 10
    • 4
    Rabbit
    Clonality
    • 55
    • 13
    Polyclonal
    Conjugate
    • 34
    • 12
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COL2 antibody is un-conjugated
    Application
    • 50
    • 37
    • 22
    • 20
    • 15
    • 13
    • 12
    • 12
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Guinea Pig, Human, Mouse, Rabbit, Rat
    Predicted Reactivity
    Dog,Cow,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Collagen II
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Chen, Kuo, Wang, Chen: "Dual Function of Glucosamine in Gelatin/Hyaluronic Acid Cryogel to Modulate Scaffold Mechanical Properties and to Maintain Chondrogenic Phenotype for Cartilage Tissue Engineering." in: International journal of molecular sciences, Vol. 17, Issue 11, (2017) (PubMed).

    Liu, Yu, Ma, Xiang, Hu, Chen: "Lentivirus-mediated TGF-β3, CTGF and TIMP1 gene transduction as a gene therapy for intervertebral disc degeneration in an in vivo rabbit model." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1399-1404, (2016) (PubMed).

    Fu, Liao, Lin, Sun, Tian, Zhu, Lin: "PCL-PEG-PCL film promotes cartilage regeneration in vivo." in: Cell proliferation, Vol. 49, Issue 6, pp. 729-739, (2016) (PubMed).

    Wang, Yang, Lin, Liu, Yang, Kuo, Chen: "Expandable Scaffold Improves Integration of Tissue-Engineered Cartilage: An In Vivo Study in a Rabbit Model." in: Tissue engineering. Part A, Vol. 22, Issue 11-12, pp. 873-84, (2016) (PubMed).

    Li, Niu, Wu, Du, Huang, Yin, Liu, Song, Leng: "Vitamin D prevents articular cartilage erosion by regulating collagen II turnover through TGF-β1 in ovariectomized rats." in: Osteoarthritis and cartilage, Vol. 24, Issue 2, pp. 345-53, (2016) (PubMed).

    Jeong, Yang, Lee, Ryoo, Kim, Oh, Kwon, Liu, Son: "Serial changes in the proliferation and differentiation of adipose-derived stem cells after ionizing radiation." in: Stem cell research & therapy, Vol. 7, Issue 1, pp. 117, (2016) (PubMed).

    Wu, Zhu, Sun, Hu: "Subchondral bone changes and chondrogenic capacity of progenitor cells from subchondral bone in the collagenase-induced temporomandibular joints osteoarthritis rabbit model." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 9782-9, (2016) (PubMed).

    Chen, Chen, Jhan, Liu, Ho, Mao, Kohn, Sheu: "Development and Characterization of Acellular Extracellular Matrix Scaffolds from Porcine Menisci for Use in Cartilage Tissue Engineering." in: Tissue engineering. Part C, Methods, (2015) (PubMed).

    Li, Fu, Xie, Fu, Deng, Cun, Wei, Peng, Cai, Lin: "Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) Based Electrospun 3D Scaffolds for Delivery of Autogeneic Chondrocytes and Adipose-Derived Stem Cells: Evaluation of Cartilage Defects in Rabbit." in: Journal of biomedical nanotechnology, Vol. 11, Issue 1, pp. 105-16, (2015) (PubMed).

    Jiang, Tian, Wang, Yan, Liu, Liu, Song, Zhang, Shen, Zhang: "Effect of calcitonin pretreatment on naturally occurring intervertebral disc degeneration in guinea pig." in: International journal of clinical and experimental medicine, Vol. 8, Issue 7, pp. 10367-79, (2015) (PubMed).

    Zheng, Sun, Li, Zhou, Fan, Zhang: "Comparative study of collagen hydrogels modified in two ways using the model of ectopic cartilage construction with diffusion-chamber in immunocompetent host." in: Journal of applied biomaterials & functional materials, Vol. 12, Issue 1, pp. 41-7, (2014) (PubMed).

    Kuo, Chen, Hsiao, Chen: "Incorporation of chitosan in biomimetic gelatin/chondroitin-6-sulfate/hyaluronan cryogel for cartilage tissue engineering." in: Carbohydrate polymers, Vol. 117, pp. 722-30, (2014) (PubMed).

    Xu, Dai, Liu, Liu, Song, Li, Chen, Lin: "Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1065-1074, (2014) (PubMed).

    Luo, Zhang, Wang, Hu, Song, Su, Zhang: "Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats." in: Bone, Vol. 55, Issue 2, pp. 439-48, (2013) (PubMed).

    Wang, Bian, Wu, Chen: "Evaluation of three-dimensional scaffolds prepared from poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for growth of allogeneic chondrocytes for cartilage repair in rabbits." in: Biomaterials, Vol. 29, Issue 19, pp. 2858-68, (2008) (PubMed).

  • Target
    COL2 (Collagen, Type II (COL2))
    Alternative Name
    Collagen 2 (COL2 Products)
    Synonyms
    PT antibody, RPRGL2 antibody, THPH1 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, prothrombin antibody, CAP18 antibody, Cnlp antibody, Cramp antibody, FALL39 antibody, MCLP antibody, coagulation factor II, thrombin antibody, coagulation factor II antibody, cathelicidin antimicrobial peptide antibody, Cuticle collagen 2 antibody, collagen type II alpha 1 chain antibody, F2 antibody, Camp antibody, col-2 antibody, COL2A1 antibody
    Background

    Synonyms: AOM, ANFH, SEDC, STL1, COL11A3, Collagen alpha-1(II) chain, Alpha-1 type II collagen, COL2A1

    Background: Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.

    Molecular Weight
    156kDa
    Gene ID
    1280
    UniProt
    P02458
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