CD81 antibody (Alexa Fluor 488)

Catalog No. ABIN6722840

The Mouse Monoclonal anti-CD81 antibody is suitable to detect CD81 in samples from Human. It has been validated for FACS.

Quick Overview for CD81 antibody (Alexa Fluor 488) (ABIN6722840)

Target: CD81

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD81 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: 1-3-3-22

Product Details anti-CD81 Antibody (Alexa Fluor 488)

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD81

Target: CD81

Alternative Name: CD81

Background:

Synonyms: CD81 antigen,CD81,26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1.Tetraspanin-28,Tspan-28,APA1, TSPAN28

Background: CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.

Gene ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C