CTGF antibody (AA 221-349) (Biotin)

Catalog No. ABIN672638

The Rabbit Polyclonal anti-CTGF antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect CTGF in samples from Human, Mouse and Rat. There is 1 publication available.

Quick Overview for CTGF antibody (AA 221-349) (Biotin) (ABIN672638)

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTGF antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CTGF Antibody (Biotin)

Binding Specificity: AA 221-349

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTGF

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-CTGF antibody (Biotin) (ABIN672638)

Gendron, Lemay, Lecours, Perreault-Vallières, Huppé, Bossé, Blanchet, Dion, Marsolais: "FTY720 promotes pulmonary fibrosis when administered during the remodelling phase following a bleomycin-induced lung injury." in: Pulmonary pharmacology & therapeutics, Vol. 44, pp. 50-56, (2017) (PubMed).

Target Details for CTGF

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Alternative Name: CTGF

Background:

Synonyms: CCN2, NOV2, HCS24, IGFBP8, Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8, CTGF

Background: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

Gene ID: 1490

UniProt: P29279

Pathways: Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding