LY6C + LY6G antibody (Alexa Fluor 488)

Catalog No. ABIN6727020

The Rat Monoclonal anti-LY6C + LY6G antibody is suitable to detect LY6C + LY6G in samples from Mouse. It has been validated for FACS.

Quick Overview for LY6C + LY6G antibody (Alexa Fluor 488) (ABIN6727020)

Target: LY6C + LY6G

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: RB6-8C5

Product Details

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details

Target: LY6C + LY6G

Alternative Name: Ly-6G/Ly-6C (Gr-1)

Background:

Synonyms: Gr-1,Gr1,Ly-6G/Ly-6C,Ly6G/Ly6C

Background: Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation, Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

Gene ID: 546644, 17067

UniProt: P35461, P0CW02, P0CW03