TIM3 antibody (Hepatitis A Virus Cellular Receptor 2) (PE)

Details for Product anti-TIM 3 Antibody No. ABIN6728493
Target
Reactivity
Mouse
79
40
3
2
2
1
1
Host
Rat
55
32
19
8
Clonality (Clone)
Monoclonal ()
Conjugate
This TIM3 antibody is conjugated to PE
10
10
10
8
5
3
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
61
56
40
20
6
6
5
4
3
3
3
2
1
Options
Clone RMT3-23
Isotype IgG2a, kappa
Target
Alternative Name CD366/Tim-3 (TIM 3 Antibody Abstract)
Background

Synonyms: TIM3, TIMD3,HAVcr-2,TIMD-3

Background: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Gene ID 84868
UniProt Q8TDQ0
Pathways Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.